Mexedrone (3-methoxy-2-(methylamino)- 1-(p-tolyl)propan-1-one) is a stimulant of the cathinone concoction class with an intensity of about 2/third of that of mexedrone.

This compound has almost no history of human utilization before its discharge in August 2015 as a recently accessible hazy area look into chemical.[1][2][3] It has been fundamentally showcased as a legitimate contrasting option to mephedrone albeit episodic reports appear to all around propose that it is generally second rate in its recreational impacts because of its weaker intensity, incitement and rapture.



Mexedrone, or 3-methoxy-2-(methylamino)- 1-(p-tolyl)propan-1-one, is a manufactured particle of the cathinone family. Cathinones are fundamentally like amphetamines. They contain a phenethylamine center highlighting a phenyl ring bound to an amino (NH2) assemble through an ethyl chain with an extra methyl substitution at Rα. Amphetamines and cathinones are alpha-methylated phenethylamines. Cathinones contain an extra ketone assemble fortified at R1.

Mexedrone contains extra methyl substitutions at RN (like MDMA and methamphetamine) and R4 of its phenyl ring. Mexedrone is named for the methoxy gathering (C3O-) bound to the methyl aggregate situated at Rα. Mexedrone is firmly closely resembling mephedrone, be that as it may, mephedrone does not have the extra methoxy assemble attached to the α-methyl gathering.


Given its comparable subjective impacts and substance structure to mephedrone, this compound is likely (however not affirmed) to go about as a discharging specialist and a reuptake inhibitor for monoamine neurotransmitters, for example, serotonin, dopamine and noradrenaline. This expansion in neurotransmitters gives a clarification to the euphoric and animating impacts prompted by this experience. Narrative reports frequently express that mexedrone is more calming than empowering, which proposes it might discharge more serotonin than dopamine in a manner that is like MDAI.

Subjective impacts

The impacts recorded beneath depend on the subjective impacts list and individual encounters of PsychonautWiki benefactors. The recorded impacts ought to be brought with a grain of salt and will once in a while (if at any time) happen at the same time, however heavier dosages will expand the odds and will probably incite a full scope of impacts. Moreover, unfriendly impacts turn out to be a great deal more probable on higher measurements and may incorporate damage or passing.